Celldeath相关论文
Within the last several decades, the scientific community has made substantial progress in elucidating the complex patho......
Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification i
Previous reports suggested that cinnamaldehyde(CA),the bioactive ingredient in Cinnamomum cassia,can suppress tumor grow......
Herein,we define the role of ferroptosis in the pathogenesis of diabetic cardiomyopathy(DCM)by examining the expression ......
The immune checkpoints,cytotoxic T-lymphocyte-associated antigen 4(CTLA-4)and pro-grammed cell death protein-1/ligand-1(......
Roles of MEM1 in safeguarding Arabidopsis genome against DNA damage,inhibiting ATM/SOG1-mediated DNA
Arabidopsis methylation elevated mutant 1 (mem1)mutants have elevated levels of global DNA meth-ylation.In this study,su......
中性粒细胞一直被认为是先天免疫系统中一种短寿命的、同质的细胞类型,具有有限的促/抗炎作用。然而最近10年,随着研究的深入,对中性......
Sepsis is a life-threatening clinical syndrome and one of the most challenging health problems in the world. Pathologica......
Cell death is an important physiological phenomenon in life. It can be programmed or unprogrammed. Unprogrammed cell dea......
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Flavonoids are polyphenolic secondary metabo-lites that function as signaling molecules, allopathic compounds, phytoalex......
Hypoxic preconditioning reduces NLRP3 inflammasome expression and protects against cerebral ischemia
Hypoxic preconditioning can protect against cerebral ischemia/reperfusion injury. However, the underlying mechanisms tha......
Lithium is associated with oxidative stress and apoptosis,but the mechanism by which lithium protects against spinal cor......
Molecular mechanism and therapeutic targeting of necrosis, apoptosis, pyroptosis, and autophagy in c
Cell death occurs in various tissues and organs in the body. It is a physiological or pathological process that has diff......
A monocot-specific hydroxycinnamoylputrescine gene cluster contributes to immunity and cell death in
Phenolamides(PAs),a diverse group of specialized metabolites,including hydroxycinnamoylputrescine(HP),hydroxycinnamoylag......
Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glu
Our previous studies showed that ferroptosis plays an important role in the acute and subacute stages of spinal cord inj......
Perinatal complications, such as asphyxia, can cause brain injuries that are often associated with subsequent neurologic......
Aim: To evaluate the protective effects of ginger (Gin) and roselle (Ros) against testicular damage and oxidative stress......
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Adenine nucleotide translocase (ANT) is a constitutive component located in the inner membrane of mitochondria involved ......
Candidate effector proteins of the necrotrophic apple canker pathogen Valsa mali can suppress BAX-in
Canker caused by the Ascomycete Valsa mali is the most destructive disease of apple in Eastern Asia, resulting in yield ......
Role of DRAM2,a Novel Damage-Regulated Autophagy Modulator (DRAM) like Protein,in Autophagic Cell De
Autophagy,the degradation of cytoplasmic components,is an evolutionarily conserved homeostatic process involved in envir......
BNIP3 Upregulation and AIF Translocation in Nucleus Pulposus Cell Death Following Nutrients Deprivat
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Naturalistic peptide receptor A inhibition suppresses gastric cancer development through reactive ox
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Cysteinyl leukotriene receptor 1 and 2 are involved in astrocyte proliferation or injury following o
Cysteinyl leukotrienes (CysLTs) are 5-1ipoxygenase (5-LOX) metabolites of arachidonic acid and exert potent pro-inflamma......
HDAC2 augments DNA damage-mediated cell death of human osteosarcoma cells through the stimulation of
To overcome the serious chemo-resistant phenotype of the advanced cancers,it is urgently required to precisely understan......
BRI1-ASSOCIATED RECEPTOR KINASE 1(BAK1)and its closest paralog,BAK1-LIKE 1(BKK1),two leucine-rich repeat receptor-like p......
3beta-hydroxysteroid-delta24 reductase protects neuronal cells against apoptosis induced by endoplas
3beta-hydroxysteroid-delta24 reductase (DHCR24) is a multifunctional enzyme with anti-apoptotic and cholesterol-synthesi......
THANATOS: an integrative data resource of proteins and post-translational modifications in the regul
Autophagy is a highly conserved process for degrading cytoplasmic contents,determines cell survival or death,and regulat......
p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and s
The inhibitory role of p53 in DNA double-strand break (DSB) repair seems contradictory to its tumor suppressing property......
Sphingosine kinase 1 (SphK1) is over-expressed in many cancers and therefore serves as a biomarker for cancer prognosis.......
Acid-sensing ion channel 1a (ASIC1a) is the key proton receptor in nervous systems, mediating acidosis-induced neuronal ......
The Targeted Inhibition of Mitochondrial Hsp90 Overcomes The Apoptosis Resistance Conferred By Bcl-2
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Selective unresponsiveness to the inhibition of p38 MAPK activation by cAMP helps L929 fibroblastoma
The cyclic AMP (cAMP) signaling pathway has been reported to either promote or suppress cell death,in a cell context-dep......
Riboflavin(vitamin B2)has been thought to be a promising antitumoral agent in photodynamic therapy,though the further ap......
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PGC-1α overexpression promotes mitochondrial biogenesis to protect auditory cells against cisplatin-
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A selective and bioactive inhibitor of cystathionine β-synthase identifies a novel regulator of ferr
Cystathionine β-synthase(CBS)and cystathionine γ-lyase(CSE)are responsible for producing hydrogen sulfide(H2S)in m......
The Targeted Inhibition of Mitochondrial Hsp90 Overcomes The Apoptosis Resistance Conferred By Bcl-2
Previous studies presented that Gamitrinibs rapidly accumulate in tumor cell mitochondria, lead cells to apoptotic p......
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γ-L-glutamyl-S-[2-[[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]carbonyl......
Bioinformatic studies of protein post-translational modifications in the regulation of autophagy and
Background: Post-translational modifications (PTMs) play an important role in the regulation of various biological p......
Identification and functional characterization of plant-specific NAC transcription factor gene famil
NAC transcription factors are plant-specific and play important roles in plant development processes, response to bi......
Programmed cell death(PCD)plays an important role for development and defenses in animals and plants.In plants,a wel......
Jag1b is essential for patterning inner ear sensory cristae by regulating anterior morphogenetic tis
In vertebrate inner ears,sensory patches,which containing hair cells and supporting cells,are essential for hearing ......
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Tapping panel dryness (TPD) is a complex physiological syndrome found widely in rubber tree (Hevea brasiliensis) pla......
Programmed cell death (PCD) is a critical biological process involved in many important functions,and defects in the......
混合谱系激酶结构域样蛋白(mixed lineage kinase domain-like protein, MLKL)是一种具有激酶结构域的假激酶,在程序性坏死的调控中......